Detailed Program

Summer School / Workshop of Molecular Computations for Systems Chemistry

University of Szeged

2009

 

1st week: June 15-June 20

Theoretical background to Computational Chemistry

Monday 15th June:

a.m. Arriving, Registration, Practical Guide, Overview of the Scientific Program

p.m. Mathematics as the Language of Electron Distribution Imre G. Csizmadia

Practice: INTRODUCTION TO USE OUR COMPUTER SYSTEM

Tuesday 16th June:

a.m. Ab initio (Hartree-Fock) Methods and Basis Sets Imre G. Csizmadia

p.m. Post Hartree-Fock Methods Béla Viskolcz

Practice: INPUT GENERATION, OUTPUTS, VISUALISATION

Wednesday 17th June:

a.m. Topology of Potential Energy Surface Imre G. Csizmadia

p.m. Geometry Optimization I. Imre G. Csizmadia

Practice: COMPUTE A POTENCIAL CURVE, AND POTENTIAL ENERGY SURFACE

Thursday 18th June:

a.m. Accurate Thermodynamic Functions Béla Viskolcz

p.m. to be announced

Practice: COMPUTE HEAT OF FORMATIONS

Friday 19th June:

a.m. Blind-Search for Transition States Béla Viskolcz

p.m. to be announced

Practice: CHARACTERIZATION OF LOCAL MINIMA AND TRANSITION STATES

2nd week: June 22-June 26

Advanced Computational Chemistry

 

Monday 22th June:

a.m. Chirality of the Potential Energy Surface Imre G. Csizmadia

p.m. Molecular Structural Information Change During Peptide Folding Béla Viskolcz

Practice: COMPUTE RELATIVE HEAT OF REACTIONS

Tuesday 23th June:

a.m. Free Radicals in Oxidation Process Béla Viskolcz

p.m. Protein Structures and Databases Balázs Jójárt

Practice: Potential energy suface of Benzene oxidation

Wednesday 24th June:

a.m. Potential Energy Functions and Force Fields for Molecular Dynamics Balázs Jójárt

p.m. Molecular docking using Autodock software Balázs Jójárt

Practice: VISUALISATION OF PROTEINS AND CONFORMATIONAL ANALYSIS BY MM&MD

Thursday 25th June:

a.m. Protein folding and misfolding modeled by peptides András Perczel

p.m.  Computational Drug Design in Practice Tímea Polgár

Practice: MOLECULAR DOCKING

Friday 26th June:

a.m. Solvent effects Zoltán Mucsi

p.m. Reaction Mechanisms by molecular computations Zoltán Mucsi  

 

 

3rd week: June 29-July 03

Advanced Computational Chemistry in Practice

 

Monday 29 June:

a.m. Conjugativities as measures of stabilization and reactivity I. Zoltán Mucsi

p.m. Conjugativities as measures of stabilization and reactivity II. Zoltán Mucsi

Practice: COMPUTE A POTENCIAL CURVE, AND POTENTIAL ENERGY SURFACE OF CHIRAL SYSTEMS

Tuesday 30th June:

a.m. Advanced Geometry Optimization Ödön Farkas

p.m. Oniom Models Ödön Farkas

Practice: COMPUTE POLYPEPTIDES CONFORMERS

Wednesday 1st July: Schrödinger Training Jas Gata-Aura

PROTEIN PREPARTION

Introduction to Docking – GLIDE

Introduction to Quatum Polarised Ligand Docking – QPLD

Introduction to Induced Fit Docking – IFD

Practice: HAND-ON SESSION

Thursday 2nd July:  Schrödinger Training Jas Gata-Aura

Introduction to Molecular Dynamics - DESMOND

Presentation, Demonstration,

Practice: HAND-ON SESSION

Friday 3rd July:

Dynamics on Self-Assembled Monolayer Milán Szőri

Topology of Electron Density Milán Szőri

Closing Remarks Imre G. Csizmadia

 

Staff:

  • Imre G. Csizmadia (University of Szeged & University of Toronto)
  • Béla Viskolcz (University of Szeged)
  • Balázs Jójárt (University of Szeged)
  • Milán Szőri (University of Szeged)
  • András Perczel (University of Eötvös Lorand) 
  • Ödön Farkas (University of Eötvös Lorand)
  • Tímea Polgár (Servier Research Institute of Medical Chemistry)
  • Zoltán Mucsi (Servier Research Institute of Medical Chemistry)